👉 Aged biology refers to the biological changes that occur as organisms age, leading to a decline in physiological functions and increased vulnerability to diseases. These changes can be observed at multiple levels, from cellular to organismal. At the cellular level, aging is marked by telomere shortening, DNA damage accumulation, mitochondrial dysfunction, and altered protein homeostasis, which collectively impair cell function and contribute to tissue degeneration. As organisms age, stem cell populations diminish, reducing the body's ability to repair and regenerate tissues. Systemically, aging affects organ systems, leading to decreased metabolic efficiency, weakened immune responses, and increased chronic inflammation. These biological processes culminate in a higher risk of age-related diseases such as cardiovascular disorders, neurodegenerative conditions, and cancer, ultimately reducing lifespan and quality of life.
