👉 Tolbutamide is a medication used to treat certain types of cancer. It works by blocking the growth and division of cancer cells, which can help slow or stop the spread of the disease. Tolbutamide has been approved for use in several different types of cancer, including breast cancer, lung cancer, and colon cancer. Tolbutamide is a synthetic drug that is made from a chemical called tolbutamine. It works by blocking the growth and division of cancer cells, which can help