👉 Simulance is a medical term used to describe a condition in which the body's immune system, especially the immune response, becomes overly active and can cause severe or life-threatening symptoms. This condition can also be referred to as an immune overreaction. It occurs when the body's immune system perceives an infection or injury as a threat and begins to produce antibodies that attack the target cells in the body. The excess production of antibodies is known as "simplification," which leads to severe inflammation and