👉 In biology, a serine is an amino acid that is part of the C-terminus of a polypeptide chain. It has two nitrogen atoms and one oxygen atom at the other end. Serine is considered a nonessential amino acid because it does not participate in any metabolic processes or provide any function in the body. It is found in many essential amino acids, such as glycine (Gly), alanine (Ala), and histidine (His).