Outrageously Funny Word Dictionary :: Painsworthy

👉 Painsworth's disease, also known as pain with a characteristic pannus (panss), is a rare genetic disorder that causes severe joint pain and weakness. It can be caused by mutations in the gene encoding for the pro-inflammatory cytokine interleukin-18 (IL-18). This cytokine plays an important role in inflammation, but if it is overproduced, it can cause joint damage and muscle weakness. Painsworth's disease is characterized by a p

painsworthy