👉 Monoplacemic refers to a condition in which the brain is incapable of producing or responding to a single impulse, such as a motor command. This can occur due to damage to specific areas within the brain's cortex, causing a complete blockage of sensory information. In other words, if you have a headache and you try to take your medication, but it doesn't work for some reason, you might say that you are "monoplacemic."