👉 Indrubine is a chemical compound that is used as an antiemetic. It is also known as indomethacin, and it is commonly used in the treatment of nausea and vomiting caused by certain causes such as chemotherapy or surgery. Indrubine works by blocking the action of a neurotransmitter called GABA (gamma-aminobutyric acid) which is involved in the regulation of mood, sleep, and arousal.