👉 Holoenzyme, also known as a heteromeric enzyme, is an enzyme that consists of two or more enzymes working together to catalyze a reaction. Holoenzymes are typically found in living organisms and are composed of one or more smaller enzymes that work in concert with each other to carry out the specific task they were designed for. These enzymes can be made up of any combination of amino acids, nucleotides, or other molecules that function as substrates or products during the reaction