👉 In medical terminology, a fibrinolytic is a type of enzyme that helps in breaking down fibrin, a protein-rich clotting factor. Fibrinolytics are enzymes that break down fibrinogen, an essential component of blood clots. They work by binding to the clotting factors V and VII (fibrinogen and plasmin) and preventing their aggregation. The term "fibrinolytic" refers to a process where these enzymes act together to break down