👉 The term "estrone" is defined as a non-steroidal anti-inflammatory drug (NSAID) that belongs to the class of cyclooxygenase inhibitors. It is commonly used in the treatment of pain and inflammation, particularly in conditions such as rheumatoid arthritis, osteoarthritis, and inflammatory bowel disease. The main mechanism by which estrones work is through their ability to inhibit the synthesis of prostaglandin E2, a substance that plays a crucial role in the