👉 The term "coagulants" refers to substances that are involved in forming and/or breaking up large molecules, such as blood cells or proteins. These substances can be either natural or artificial. Natural coagulants include clotting factors from red blood cells, fibrinogen from platelets, and factor Xa from activated plasma. Artificial coagulants are produced by various sources including biological systems like the liver, kidney, and spleen, as well as synthetic compounds used in medicine