👉 Arecolide is a prescription medication used for the treatment of colitis, an inflammation of the small intestine. It works by blocking the action of the p-glycoprotein (GPP) transporter in the colon. This blocks the absorption of nutrients and water into the bloodstream, leading to diarrhea, abdominal pain, and constipation. The drug is typically prescribed as a single dose (usually 10 mg) at bedtime for symptomatic relief from symptoms such as loose stools, bloating,