👉 The um fluid, also known as pre-eclampsia-related protein (PR-P) or soluble endoglin 2 (sEng-2), is a protein complex that plays a significant role in the pathogenesis of pre-eclampsia, a serious pregnancy complication characterized by high blood pressure and damage to organs. Elevated levels of um fluid are typically detected in the second or third trimester of pregnancy and are associated with endothelial dysfunction, inflammation, and oxidative stress. These factors contribute to the clinical manifestations of pre-eclampsia, such as hypertension and proteinuria. Understanding the role of um fluid in pre-eclampsia has led to improved diagnostic tools and potential therapeutic targets for managing this condition.
