👉 Synedrosphenia is a condition characterized by an increased risk of developing osteoporosis, particularly in women who are older than 50 years old and have a family history of osteoporosis or other bone disorders. It is caused by a deficiency in the enzyme ceruloplasmin, which is involved in the breakdown of collagen, a protein that provides structural support to bones. This condition can lead to increased risk of fractures and osteopenia (weakness and reduced bone density),