👉 In the context of biochemistry, "semi-occlusive" refers to a protein molecule that is not fully occluded by its active site. This allows it to interact with ligands or other molecules without completely blocking its activity. For example, in the enzyme catalase (also known as peroxidase), when an oxidant like hydrogen peroxide binds to the active site of the enzyme, it partially occludes it from binding to its substrate. However, once the oxidant is gone,