👉 Sickle cell anemia, characterized by a defective hemoglobin protein responsible for oxygen transport in red blood cells. It is caused by mutations in the gene encoding hemoglobin that results in a defect in the synthesis and release of the hemoglobin molecule from the red blood cell. This can lead to a condition known as sickle cell disease where the red blood cell has a distinctive, sickle-shaped appearance and the blood volume is reduced.
SBV