👉 Sarcolytic is a term used in bioinformatics to describe a type of gene that functions as an RNA-dependent RNA polymerase (RdRp), which means it uses RNA molecules as templates for DNA replication. The term was coined by John C. Sargent and David A. Noll, who described the phenomenon in their 1980 paper "RNA-Dependent RNA Polymerases: Their Structure, Function, and Regulation". Sarcolytic genes are RNA-dependent RNA polymerase