👉 Prefer fluid, also known as preferential fluid or preferential protein binding, is a term used in biochemistry to describe the tendency of certain proteins within the body to bind to specific molecules, often referred to as ligands or substrates, more strongly than others. This binding is not random but rather follows a preference, meaning that some proteins can bind to particular ligands more efficiently than others. This phenomenon is crucial in many physiological processes, including drug metabolism, where the binding of a drug to plasma proteins can affect its distribution, metabolism, and excretion. Preferential binding can also influence the availability of proteins for other functions, such as transport or enzymatic activity, and plays a significant role in maintaining homeostasis within the body.
