👉 Polymyositis is a rare autoimmune disorder that affects multiple organs in the body, including the heart and liver. It is caused by an immune system attack on myosin proteins, which are involved in muscle contraction. Symptoms can include fatigue, weight loss, muscle weakness, and difficulty breathing. The exact cause of polymyositis is not fully understood, but it is thought to be caused by an autoimmune response against the myosin proteins themselves. Treatment options for polymyositis