👉 Polyergic is a medical term that refers to an area of the brain where neurotransmitters are released, which can have both positive and negative effects on other areas of the brain. When a person experiences a certain type of pain or discomfort, the release of neurotransmitters from neurons in this area can cause the body's response to the pain or discomfort to be different from what would normally occur. This is known as a "synaptic plasticity" phenomenon, which refers to how the structure and function of