👉 Periostosis is a condition in which the cells in the bone, called osteoblasts, are not properly growing and dividing. This can lead to the formation of abnormal bones or tumors. The exact cause of periosteal failure is not fully understood but it might be related to genetics or environmental factors such as exposure to radiation or trauma. It's also possible that some people may have a genetic mutation that causes them to have this condition. Periosteal failure can lead to bone