👉 A monopox virus is an RNA-based virus that was first isolated from a human patient with severe pneumonia in 1968. It has been identified as the causative agent of mononucleosis, which is caused by viruses like Epstein-Barr virus (EBV). Monexpicoviruses are known for their ability to cause acute respiratory distress syndrome (ARDS) and have been associated with increased mortality rates in patients with severe pneumonia.