👉 Melanodexia, also known as skin melanin deficiency, is a rare genetic disorder characterized by a lack of melanin in the skin and hair. This condition can lead to various health problems such as sunburn, acne, and dryness. It's caused by a mutation in the Y-linked gene encoding melanosomes, which are responsible for producing and maintaining melanin. Treatment options vary, including phototherapy, oral medications, and perhaps surgical procedures if severe.