👉 Macrodactylism is a rare genetic disorder characterized by an abnormal shape of the fingers, called macroskull, which can be either flat or crooked. This condition is caused by a mutation in the gene encoding for the alpha subunit of the nerve cell body complex, which is involved in the development and function of muscles. Macrodactylism affects approximately 1 in every 20,000 people worldwide, with cases being more common in Asian populations. It can