👉 Leptomeningitis is a type of meningitis characterized by inflammation of the meninges, or membranes surrounding the brain and spinal cord. In this condition, the meninges are inflamed, which can cause symptoms such as fever, headache, neck stiffness, and fatigue. The exact mechanisms underlying leptomeningitis vary depending on the individual affected, but it is often due to an infection or immune response that damages the lining of the meninges.