👉 Hypophrenous disease, also known as pituitary adenoma, is a condition in which the pituitary gland becomes enlarged and inflamed. It can cause symptoms such as nausea, vomiting, or difficulty breathing when there's too much fluid in the blood vessels within the pituitary gland. This condition typically affects females more than males due to hormonal differences between them. In women, it is also known as amenorrhea (abnormal menstruation), which can affect fertility and