👉 In medicine, a hypaethral is a small, hollow space near the base of the skull. It is usually found in the brain and may be used as an area to treat certain conditions. hypaethral, n., vt. (to) (1) (n.) A narrow space in the front of the skull that is filled with air. An example: The hypaethral space is a small, hollow space near the base of the skull.