👉 Hepatophyma is a rare genetic disorder that affects the liver, causing it to swell and become inflamed. The disease typically begins in childhood and can lead to serious complications if left untreated. There is currently no cure for hepato-ferdinandian syndrome (HFS), but there are treatments available to manage symptoms and improve quality of life. The exact cause of this disorder is not known, but it is thought to be caused by mutations in the alpha-fetoprotein