👉 The term "epineurium" is defined as a small, fluid-filled sac or pocket that forms in the brain and spinal cord surrounding the brain stem. It is primarily responsible for protecting the brain from damage by preventing the leakage of cerebrospinal fluid (CSF) into the brain. The epineurium acts as a barrier that prevents the CSF from leaking out of the brain, which can cause swelling or pressure in the brain and spinal cord, leading to symptoms such as