👉 Endo-polyplasticity refers to a condition in which cells, including human cells, undergo an irreversible process that leads to the formation of two daughter cells with identical genetic material. This process is called endo- or heterokaryonogenesis. Endo-polyplasticity can occur spontaneously or through somatic mutations, and it has been observed in various cell types, including hematopoietic stem cells, neural crest cells, and embryonic stem cells (ESCs). It