👉 The baseline fluid, also known as total protein-free plasma (TPFP), serves as a fundamental reference point in clinical diagnostics. It represents the plasma component that excludes proteins, such as albumin, globulins, and fibrinogen, to provide a baseline measure of the total protein content without the confounding effects of these proteins. This measurement is crucial for assessing hydration status, monitoring renal function, and evaluating the overall protein balance in the body. By comparing a patient's baseline fluid to subsequent measurements, healthcare providers can detect changes indicative of various conditions, such as dehydration, liver dysfunction, or kidney impairment.