👉 Cooperman's disease is a rare genetic disorder that affects the central nervous system, affecting the motor cortex and causing seizures. It typically occurs in individuals who inherit mutations in the CooperMann complex (COMC) gene, which encodes for alpha-2 adrenergic receptors. The syndrome presents with symptoms of tremors, rigidity, and seizures, often associated with a reduction in the number of alpha-2 adrenergic receptors, known as alpha-2-receptor deficiency
