Definition: Swainson's disease, also known as Schizosaccharomyces pombe disease or pellagra, is a genetic disorder that affects the nervous system and can lead to severe neurological symptoms such as weakness, numbness, and tingling in the hands and feet. It is caused by a deficiency of the enzyme, xanthine oxidase, which breaks down essential amino acids, including lysine, arginine, and methionine, into their respective derivatives and causes the body