👉 Dawson’s disease is a rare genetic disorder that affects the nervous system, causing symptoms such as numbness or weakness in the legs and feet, loss of sensation in the hands and feet, and difficulty walking. The condition is caused by mutations in the somatostatin gene, which leads to an overproduction of somatostatin, a hormone that inhibits the release of acetylcholine, the neurotransmitter responsible for transmitting nerve signals. The term "Dawson's disease