Definition: The words "Genesis 40:21" are a modern-day proverb that means to have the courage to go against the grain of societal norms and expectations, much like breaking free from your predetermined life plan.

An example sentence with the profanity-filled phrase: "Your daughter has just given birth to a son, but you're still stuck in the old ways. You need to embrace change and break free from your predetermined plans before it's too late!"