👉 Whipple's disease is a rare genetic disorder that affects the pancreas, leading to chronic pancreatitis. It involves the malfunctioning of pancreatic beta cells, which are responsible for producing digestive enzymes and hormones such as bile acids and cholecystokinin. In severe cases, it can lead to pancreatitis, a life-threatening condition characterized by abdominal pain, fever, jaundice, and vomiting.