👉 Tattersall's, also known as Tattersalls' disease, is a rare genetic condition that affects the skin and nails. It causes thickening of the skin, called keratosis, which can lead to peeling and scarring. The condition is often caused by mutations in the T-cell receptor (TCR), an important molecule involved in immune response and cell-to-cell communication. Treatment options for Tattersall's typically include immunosuppressive therapy and surgery if no other treatment is