👉 Hosmer's method, also known as Hosmer-Lemeshow test, is a statistical test used in bioinformatics for comparing two gene expression datasets. It compares the log2-transformed normalized copy number values of two sets of genes and determines if there are significant differences between them based on their log2-transformed copy number ratios. This method can be applied to compare differentially expressed genes (DEGs) across multiple biological processes or conditions, helping in identifying potential biomarkers for disease diagnosis
