👉 Hemichromatopsia is a rare genetic condition characterized by a single, extremely small (1.5-3.0 mm) round pigment in the skin or hair that appears to be brownish-black and has no other coloration. This pigment is often referred to as hemichromatin, which is a term used to describe the presence of one pigment in a cell's cytoplasm. Hemichromatopsia can occur due to genetic mutations or environmental factors such as