👉 Arnoux's disease is a genetic disorder that affects the nervous system, characterized by progressive loss of motor function in the limbs and a lack of sensory perception. It is caused by mutations in the ARN2 gene, which encodes for the alpha subunit of the myelin basic protein (MBP) complex. This mutation leads to abnormal membrane formation and disorganization, resulting in damage to the axons and neurons involved in motor function.
